Several points of potential contamination exist during routine blood culture collection.
Reducing Blood Culture Contamination Starts at Collection
Blood culture contamination can lead to unnecessary treatment, increased resource utilization, and operational burden across hospitals.
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Cry Wolf: Consequences of false positive blood cultures
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Approximately 1/3 of all positive blood cultures are false positive
At a 3%11 contamination rate, roughly 1 in 3 positive results may be false.
< 1% is now achievable.
Why are blood cultures contaminated?
1
Sources of contamination
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The most common contaminant
Skin microbes reside both on the surface and deep within the epidermis, which may not be accessible to skin antisepsis. Cored by the needle, these contaminants may travel into the blood specimen during venipuncture.


